STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SYNJ2Synaptojanin-2. (985 aa)    
Predicted Functional Partners:
ITSN2
LOW QUALITY PROTEIN: intersectin-2.
    
 
 0.924
BIN1
Myc box-dependent-interacting protein 1 isoform X14.
    
 
 0.851
EPS15
Epidermal growth factor receptor substrate 15.
    
 
 0.814
DNM1
Dynamin-1-like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
    
 
 0.770
AMPH
Amphiphysin.
    
 
 0.755
SH3GL2
endophilin-A1.
    
 
 0.741
ITSN1
Intersectin-1 isoform X2.
    
 
 0.733
ENSUMAP00000027695
annotation not available
    
 
 0.733
SH3GL1
endophilin-A2.
    
 
 0.695
INPPL1
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2.
    
0.662
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.