PROSER2 protein (Ursus maritimus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

PROSER2

Proline and serine-rich protein 2. (461 aa)

Predicted Functional Partners:

NUDT5

0.636

ECHDC3

0.600

CDC123

0.597

DHTKD1

0.587

USP6NL

0.567

CCDC3

0.527

TMEM220

0.519

SYNGR4

0.518

WDPCP

0.517

WHAMM

0.508

Your Current Organism:

Ursus maritimus

NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCDC3	NUDT5	ENSUMAP00000018084	ENSUMAP00000017940	Coiled-coil domain-containing protein 3.	ADP-sugar pyrophosphatase; Belongs to the Nudix hydrolase family.	0.455
CCDC3	PROSER2	ENSUMAP00000018084	ENSUMAP00000017629	Coiled-coil domain-containing protein 3.	Proline and serine-rich protein 2.	0.527
CDC123	DHTKD1	ENSUMAP00000017948	ENSUMAP00000017873	Cell division cycle protein 123 homolog; Required for S phase entry of the cell cycle. Belongs to the CDC123 family.	Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial.	0.522
CDC123	ECHDC3	ENSUMAP00000017948	ENSUMAP00000017627	Cell division cycle protein 123 homolog; Required for S phase entry of the cell cycle. Belongs to the CDC123 family.	enoyl-CoA hydratase domain-containing protein 3, mitochondrial isoform X1.	0.511
CDC123	NUDT5	ENSUMAP00000017948	ENSUMAP00000017940	Cell division cycle protein 123 homolog; Required for S phase entry of the cell cycle. Belongs to the CDC123 family.	ADP-sugar pyrophosphatase; Belongs to the Nudix hydrolase family.	0.741
CDC123	PROSER2	ENSUMAP00000017948	ENSUMAP00000017629	Cell division cycle protein 123 homolog; Required for S phase entry of the cell cycle. Belongs to the CDC123 family.	Proline and serine-rich protein 2.	0.597
CDC123	USP6NL	ENSUMAP00000017948	ENSUMAP00000017595	Cell division cycle protein 123 homolog; Required for S phase entry of the cell cycle. Belongs to the CDC123 family.	USP6 N-terminal-like protein.	0.446
DHTKD1	CDC123	ENSUMAP00000017873	ENSUMAP00000017948	Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial.	Cell division cycle protein 123 homolog; Required for S phase entry of the cell cycle. Belongs to the CDC123 family.	0.522
DHTKD1	ECHDC3	ENSUMAP00000017873	ENSUMAP00000017627	Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial.	enoyl-CoA hydratase domain-containing protein 3, mitochondrial isoform X1.	0.506
DHTKD1	NUDT5	ENSUMAP00000017873	ENSUMAP00000017940	Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial.	ADP-sugar pyrophosphatase; Belongs to the Nudix hydrolase family.	0.547
DHTKD1	PROSER2	ENSUMAP00000017873	ENSUMAP00000017629	Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial.	Proline and serine-rich protein 2.	0.587
DHTKD1	USP6NL	ENSUMAP00000017873	ENSUMAP00000017595	Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial.	USP6 N-terminal-like protein.	0.446
ECHDC3	CDC123	ENSUMAP00000017627	ENSUMAP00000017948	enoyl-CoA hydratase domain-containing protein 3, mitochondrial isoform X1.	Cell division cycle protein 123 homolog; Required for S phase entry of the cell cycle. Belongs to the CDC123 family.	0.511
ECHDC3	DHTKD1	ENSUMAP00000017627	ENSUMAP00000017873	enoyl-CoA hydratase domain-containing protein 3, mitochondrial isoform X1.	Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial.	0.506
ECHDC3	NUDT5	ENSUMAP00000017627	ENSUMAP00000017940	enoyl-CoA hydratase domain-containing protein 3, mitochondrial isoform X1.	ADP-sugar pyrophosphatase; Belongs to the Nudix hydrolase family.	0.534
ECHDC3	PROSER2	ENSUMAP00000017627	ENSUMAP00000017629	enoyl-CoA hydratase domain-containing protein 3, mitochondrial isoform X1.	Proline and serine-rich protein 2.	0.600
ECHDC3	USP6NL	ENSUMAP00000017627	ENSUMAP00000017595	enoyl-CoA hydratase domain-containing protein 3, mitochondrial isoform X1.	USP6 N-terminal-like protein.	0.519
NUDT5	CCDC3	ENSUMAP00000017940	ENSUMAP00000018084	ADP-sugar pyrophosphatase; Belongs to the Nudix hydrolase family.	Coiled-coil domain-containing protein 3.	0.455
NUDT5	CDC123	ENSUMAP00000017940	ENSUMAP00000017948	ADP-sugar pyrophosphatase; Belongs to the Nudix hydrolase family.	Cell division cycle protein 123 homolog; Required for S phase entry of the cell cycle. Belongs to the CDC123 family.	0.741
NUDT5	DHTKD1	ENSUMAP00000017940	ENSUMAP00000017873	ADP-sugar pyrophosphatase; Belongs to the Nudix hydrolase family.	Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial.	0.547