STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTPN4Tyrosine-protein phosphatase non-receptor type; May act at junctions between the membrane and the cytoskeleton. (926 aa)    
Predicted Functional Partners:
GRIN2A
Glutamate receptor ionotropic, NMDA 2A.
    
 
 0.829
MAPK12
Mitogen-activated protein kinase.
    
 0.558
KLHL29
Kelch-like protein 29.
      
 0.546
GRB2
Growth factor receptor-bound protein 2.
   
 0.526
SLC16A7
Monocarboxylate transporter 2.
      
 0.519
MAPK13
Mitogen-activated protein kinase.
    
 0.497
MAPK14
Mitogen-activated protein kinase.
    
 0.497
LOC103660548
Oxysterol-binding protein; Belongs to the OSBP family.
      
 0.495
NFE2L3
Nuclear factor erythroid 2-related factor 3.
      
 0.491
SHC3
SHC-transforming protein 3 isoform X2.
   
 0.474
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.