STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ERC1ELKS/Rab6-interacting/CAST family member 1 isoform X1. (1132 aa)    
Predicted Functional Partners:
RIMS2
Regulating synaptic membrane exocytosis protein 2 isoform X1.
    
 
 0.798
ZFPL1
Zinc finger protein-like 1.
      
 0.797
RAD9A
Cell cycle checkpoint control protein; Belongs to the rad9 family.
      
 0.787
ADSL
Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
      
 0.778
DBN1
LOW QUALITY PROTEIN: drebrin.
    
 
 0.737
PRAME
Melanoma antigen preferentially expressed in tumors-like.
    
 
 0.734
PPFIA2
Liprin-alpha-2 isoform X1.
    
 
 0.725
GOLGB1
Golgin subfamily B member 1.
    
 
 0.721
GIT1
ARF GTPase-activating protein GIT1.
    
 
 0.720
IKBKG
NF-kappa-B essential modulator.
    
 0.686
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.