STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NLRP1NACHT, LRR and PYD domains-containing protein 1. (1436 aa)    
Predicted Functional Partners:
MEFV
Pyrin isoform X1.
   
 0.857
LOC103662442
Caspase-13-like isoform X1; Belongs to the peptidase C14A family.
   
 0.790
BCL2L1
Bcl-2-like protein 1 isoform X1.
    
 0.766
PYCARD
Apoptosis-associated speck-like protein containing a CARD isoform X1.
   
0.704
NLRP6
NACHT, LRR and PYD domains-containing protein 6.
     
0.634
BCL2
Apoptosis regulator Bcl-2.
    
 0.589
DPP8
Dipeptidyl peptidase 8 isoform X1; Belongs to the peptidase S9B family.
   
 
 0.573
DPP9
Dipeptidyl peptidase 9; Belongs to the peptidase S9B family.
   
 
 0.568
RIPK2
LOW QUALITY PROTEIN: receptor-interacting serine/threonine-protein kinase 2.
   
 0.523
GSDMD
gasdermin-D isoform X1.
      
 0.520
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.