STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BMI1Polycomb complex protein BMI-1. (326 aa)    
Predicted Functional Partners:
RNF2
E3 ubiquitin-protein ligase RING2 isoform X1.
   
 0.999
RING1
E3 ubiquitin-protein ligase RING1.
   
 0.998
CBX8
Chromobox protein homolog 8.
    
 0.990
SCMH1
Polycomb protein SCMH1 isoform X3.
   
 0.974
PCGF2
Polycomb group RING finger protein 2 isoform X1.
  
 
0.948
RYBP
RING1 and YY1-binding protein.
    
 0.931
EZH2
Enhancer of zeste 2 polycomb repressive complex 2 subunit.
    
 0.917
CBX7
Chromobox protein homolog 7.
    
 0.913
SUZ12
Polycomb protein SUZ12.
   
 0.867
LGR5
Leucine-rich repeat-containing G-protein coupled receptor 5.
   
  
 0.867
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.