STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSUMAP00000018664annotation not available (401 aa)    
Predicted Functional Partners:
LDLRAP1
Low density lipoprotein receptor adapter protein 1.
    
 0.916
DAB2
Disabled homolog 2 isoform X1.
    
 0.903
LRP6
Low-density lipoprotein receptor-related protein 6 isoform X1.
 
  
0.891
LRP5
Low-density lipoprotein receptor-related protein 5.
 
  
0.861
ANKRA2
Ankyrin repeat family A protein 2.
    
 0.823
AGRN
Agrin.
   
 0.812
CUBN
Cubilin.
   
 0.703
GC
Vitamin D-binding protein.
    
 0.592
ITSN2
LOW QUALITY PROTEIN: intersectin-2.
    
 0.581
EGF
Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.
 
   
 0.578
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.