STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SRCAPHelicase SRCAP. (3242 aa)    
Predicted Functional Partners:
RUVBL2
RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.
   
 0.942
RUVBL1
RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.
    
 0.926
VPS72
Vacuolar protein sorting-associated protein 72 homolog.
    
 0.904
DMAP1
DNA methyltransferase 1-associated protein 1.
   
 0.899
ACTR6
Actin-related protein 6 isoform X2; Belongs to the actin family.
    
 
 0.897
YEATS4
YEATS domain-containing protein 4 isoform X1.
    
 0.893
EP300
LOW QUALITY PROTEIN: histone acetyltransferase p300.
   
 0.890
TRRAP
LOW QUALITY PROTEIN: transformation/transcription domain-associated protein; Belongs to the PI3/PI4-kinase family.
   
 0.873
RBX1
E3 ubiquitin-protein ligase RBX1.
   
  0.850
ARID1A
AT-rich interactive domain-containing protein 1A isoform X1.
   
 
 0.845
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
Server load: low (12%) [HD]