STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HIGD1BHIG1 hypoxia inducible domain family member 1B. (99 aa)    
Predicted Functional Partners:
FAM187A
Ig-like V-type domain-containing protein FAM187A.
      
 0.776
COX3
Cytochrome c oxidase subunit 3; Subunits I, II and III form the functional core of the enzyme complex.
    
 
 0.580
COX2
Cytochrome c oxidase subunit 2; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1.
    
 
 0.574
ENSUMAP00000001237
annotation not available
   
  
 0.496
LIMCH1
LOW QUALITY PROTEIN: LIM and calponin homology domains-containing protein 1.
   
  
 0.496
FAM162B
Protein FAM162B.
   
  
 0.484
COX4I2
Cytochrome c oxidase subunit 4 isoform 2, mitochondrial isoform X1.
   
 
 0.471
ENSUMAP00000018943
annotation not available
   
  
 0.470
ENSUMAP00000018955
annotation not available
   
  
 0.470
PDZD2
LOW QUALITY PROTEIN: PDZ domain-containing protein 2.
   
  
 0.470
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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