STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CYYR1Cysteine and tyrosine-rich protein 1. (227 aa)    
Predicted Functional Partners:
COL8A2
LOW QUALITY PROTEIN: collagen alpha-2(VIII) chain.
   
  
 0.771
CD200
OX-2 membrane glycoprotein-like.
      
 0.568
CLEC14A
C-type lectin domain family 14 member A.
   
  
 0.542
ZP4
Zona pellucida sperm-binding protein 4.
      
 0.524
TMED6
Transmembrane emp24 domain-containing protein 6.
      
 0.518
PKP3
Plakophilin-3.
      
 0.511
HSPB6
LOW QUALITY PROTEIN: heat shock protein beta-6; Belongs to the small heat shock protein (HSP20) family.
   
  
 0.476
SPARCL1
SPARC-like protein 1 isoform X2.
   
    0.474
TCF21
Transcription factor 21.
   
  
 0.469
PPIP5K1
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...]
      
 0.457
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.