STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ESYT3Extended synaptotagmin-3. (834 aa)    
Predicted Functional Partners:
ESYT1
Extended synaptotagmin-1.
  
 
0.941
ESYT2
Extended synaptotagmin-2.
  
 
 
0.938
ORAI1
Calcium release-activated calcium channel protein 1.
      
 0.771
KCNJ15
Potassium voltage-gated channel subfamily J member 15.
      
 0.734
BLOC1S4
Biogenesis of lysosome-related organelles complex 1 subunit 4.
      
 0.731
STIM1
Stromal interaction molecule 1 isoform X1.
    
 
 0.718
ERG
Transcriptional regulator ERG isoform X1.
   
  
 0.640
SUSD3
Sushi domain-containing protein 3.
      
 0.636
C22orf31
Uncharacterized protein C22orf31 homolog.
      
 0.599
ITSN2
LOW QUALITY PROTEIN: intersectin-2.
    
0.586
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.