STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSUMAP00000020474annotation not available (685 aa)    
Predicted Functional Partners:
MPP5
MAGUK p55 subfamily member 5 isoform X1; Belongs to the MAGUK family.
    
 0.917
AMOT
Angiomotin.
    
 
 0.725
PLCB4
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
   
   0.603
AMOTL1
Angiomotin-like protein 1.
    
 
 0.595
CASK
Peripheral plasma membrane protein CASK; Belongs to the MAGUK family.
   
 0.546
PRKCZ
Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
    
 0.540
CRB1
Protein crumbs homolog 1.
    
 
 0.506
IFT57
Intraflagellar transport protein 57 homolog.
    
 0.505
MPP3
MAGUK p55 subfamily member 3; Belongs to the MAGUK family.
    
 0.502
RASSF8
Ras association domain-containing protein 8.
    
 
 0.496
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.