STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RNF135E3 ubiquitin-protein ligase RNF135. (260 aa)    
Predicted Functional Partners:
DDX58
Probable ATP-dependent RNA helicase DDX58 isoform X1.
   
 0.935
LMAN2L
Lectin, mannose binding 2 like.
   
 
 0.848
CRTC2
CREB-regulated transcription coactivator 2 isoform X1.
    
 
 0.641
RTP2
LOW QUALITY PROTEIN: receptor-transporting protein 2.
   
  
 0.601
KCTD17
Potassium channel tetramerization domain containing 17.
      
 0.598
KCTD5
BTB/POZ domain-containing protein KCTD5.
      
 0.598
C9orf64
Queuosine salvage protein; Involved in salvaging queuosine.
    
 
 0.575
TMEM218
Transmembrane protein 218.
      
 0.574
IFIH1
Interferon-induced helicase C domain-containing protein 1 isoform X1.
   
 0.564
KATNAL2
Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.
    
 
 0.543
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.