STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DECR12,4-dienoyl-CoA reductase, mitochondrial isoform X1. (323 aa)    
Predicted Functional Partners:
FPGS
Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.
   
 
 0.796
AUH
methylglutaconyl-CoA hydratase, mitochondrial; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 0.796
AADAT
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial isoform X1.
   
  
 0.735
ECI1
enoyl-CoA delta isomerase 1, mitochondrial; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 0.701
QDPR
Quinoid dihydropteridine reductase.
   
 
 0.674
ACAA2
3-ketoacyl-CoA thiolase, mitochondrial isoform X1; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.667
ECI2
enoyl-CoA delta isomerase 2, mitochondrial.
  
 0.637
HADHA
Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 0.620
CRAT
Carnitine O-acetyltransferase; Belongs to the carnitine/choline acetyltransferase family.
   
 0.615
CEP63
Centrosomal protein of 63 kDa isoform X1.
      
 0.598
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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