STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZNF488Zinc finger protein 488. (324 aa)    
Predicted Functional Partners:
COPS7B
COP9 signalosome complex subunit 7b isoform X1.
    
 0.472
NALCN
LOW QUALITY PROTEIN: sodium leak channel non-selective protein.
     
 0.462
PLCH1
Phosphoinositide phospholipase C.
    
 
 0.457
VPS45
Vacuolar protein sorting-associated protein 45; Belongs to the STXBP/unc-18/SEC1 family.
      
 0.453
TBC1D16
TBC1 domain family member 16.
      
 0.453
TMEM108
Transmembrane protein 108.
      
 0.453
EPB41L4A
Band 4.1-like protein 4A.
      
 0.453
SORCS3
VPS10 domain-containing receptor SorCS3.
    
 
 0.416
PDE11A
Phosphodiesterase.
    
 0.407
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.