STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLSCR3Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family. (220 aa)    
Predicted Functional Partners:
CHERP
Calcium homeostasis endoplasmic reticulum protein.
      
 0.601
XKR8
XK-related protein.
      
 0.601
ANO6
Anoctamin.
      
 0.529
SGK2
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
   
  
 0.525
ZCCHC13
Zinc finger CCHC domain-containing protein 13.
    
 
 0.521
NENF
Neudesin isoform X1; Belongs to the cytochrome b5 family.
      
 0.457
AKAP13
A-kinase anchor protein 13.
      
 0.456
TPMT
Thiopurine S-methyltransferase isoform X1.
    
 
 0.456
ATP11C
Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
      
 0.454
LOC103670380
LOW QUALITY PROTEIN: histidine triad nucleotide-binding protein 1-like.
      
 0.453
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.