STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103678998Inhibitor of carbonic anhydrase-like isoform X2; Belongs to the transferrin family. (655 aa)    
Predicted Functional Partners:
TFRC
Transferrin receptor protein 1 isoform X1.
  
 0.990
TF
LOW QUALITY PROTEIN: serotransferrin-like.
  
  
 
0.901
TFR2
LOW QUALITY PROTEIN: transferrin receptor protein 2.
  
 0.716
AHSG
alpha-2-HS-glycoprotein.
   
  
 0.646
ALB
Serum albumin isoform X1.
   
  
 0.601
EPO
LOW QUALITY PROTEIN: erythropoietin.
  
 0.552
LOC103673599
Haptoglobin; As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway.
   
 0.526
TTR
Transthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.
   
 
 0.524
KCTD4
Potassium channel tetramerization domain containing 4.
      
 0.519
GC
Vitamin D-binding protein.
   
 
 0.508
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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