STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TFIP11Tuftelin-interacting protein 11; Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP- containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extrac [...] (818 aa)    
Predicted Functional Partners:
DHX15
Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15.
   
 0.997
CDC40
pre-mRNA-processing factor 17.
   
 0.980
SYF2
pre-mRNA-splicing factor SYF2 isoform X1.
    
  0.962
CRNKL1
Crooked neck pre-mRNA splicing factor 1.
   
   0.962
GCFC2
GC-rich sequence DNA-binding factor 2.
    
 0.959
BUD31
Protein BUD31 homolog.
    
 
 0.958
EFTUD2
116 kDa U5 small nuclear ribonucleoprotein component.
   
 
 0.955
PRPF8
pre-mRNA-processing-splicing factor 8.
    
 
 0.940
SNRPA1
Small nuclear ribonucleoprotein polypeptide A.
    
 
 0.910
DQX1
ATP-dependent RNA helicase DQX1.
   
 0.889
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.