STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARHGAP12Rho GTPase-activating protein 12 isoform X3. (792 aa)    
Predicted Functional Partners:
PHF3
PHD finger protein 3.
      
 0.757
HAUS8
HAUS augmin-like complex subunit 8.
      
 0.752
RNF182
E3 ubiquitin-protein ligase RNF182.
     
 0.659
TBC1D30
TBC1 domain family member 30.
      
 0.655
RABGEF1
Rab5 GDP/GTP exchange factor isoform X2.
    
 
 0.643
LHFPL2
Lipoma HMGIC fusion partner-like 2 protein.
      
 0.642
RASGEF1B
ras-GEF domain-containing family member 1B.
   
  
 0.641
PIP4P1
Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P).
      
 0.637
MAP3K11
Mitogen-activated protein kinase kinase kinase 11.
   
 0.603
RHOV
LOW QUALITY PROTEIN: rho-related GTP-binding protein RhoV.
   
 0.593
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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