STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
S1PR3Sphingosine 1-phosphate receptor 3; Belongs to the G-protein coupled receptor 1 family. (378 aa)    
Predicted Functional Partners:
GNA12
Guanine nucleotide-binding protein subunit alpha-12.
    
 0.947
GNA13
Guanine nucleotide-binding protein subunit alpha-13.
    
 0.945
GNAI3
Guanine nucleotide-binding protein G(K) subunit alpha.
    
 0.942
GNAI1
Guanine nucleotide-binding protein G(I) subunit alpha-1.
    
 0.942
S1PR2
Sphingosine 1-phosphate receptor 2; Belongs to the G-protein coupled receptor 1 family.
     
0.942
S1PR1
Sphingosine 1-phosphate receptor 1; Belongs to the G-protein coupled receptor 1 family.
  
 
0.941
GNAQ
Guanine nucleotide-binding protein G(Q) subunit alpha.
 
  
 0.930
HBEGF
Proheparin-binding EGF-like growth factor.
     
 0.770
SPHK2
Sphingosine kinase 2.
      
 0.642
SPHK1
LOW QUALITY PROTEIN: sphingosine kinase 1.
      
 0.636
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.