STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAB5BRAB5B, member RAS oncogene family. (215 aa)    
Predicted Functional Partners:
PIK3C3
Phosphatidylinositol 3-kinase catalytic subunit type 3.
    
 0.958
RIN1
Ras and Rab interactor 1.
    
 0.933
RABGEF1
Rab5 GDP/GTP exchange factor isoform X2.
   
 0.932
RAB5C
Ras-related protein Rab-5C.
  
  
0.930
RAB5A
RAB5A, member RAS oncogene family.
  
  
 
0.920
EEA1
Early endosome antigen 1.
    
 0.891
APPL2
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.
   
 
 0.831
APPL1
DCC-interacting protein 13-alpha.
   
 
 0.829
RBSN
Rabenosyn, RAB effector.
   
 0.790
GAPVD1
GTPase-activating protein and VPS9 domain-containing protein 1 isoform X3.
    
 0.784
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.