STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HMOX1Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (264 aa)    
Predicted Functional Partners:
HMOX2
Heme oxygenase 2.
  
  
 
0.929
POR
NADPH--cytochrome P450 reductase.
    
 
 0.874
HM13
Minor histocompatibility antigen H13.
     
 0.860
NFE2L2
Nuclear factor erythroid 2-related factor 2 isoform X2.
     
 0.836
KEAP1
Kelch-like ECH-associated protein 1.
      
 0.823
NQO1
NAD(P)H dehydrogenase [quinone] 1.
      
 0.772
GCLC
Glutamate--cysteine ligase catalytic subunit.
    
 
 0.771
GPX1
Glutathione peroxidase 1.
    
 
 0.758
GCLM
Glutamate--cysteine ligase regulatory subunit.
      
 0.745
CASP3
Caspase-3 isoform X1; Belongs to the peptidase C14A family.
      
 0.732
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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