STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IQSEC2IQ motif and SEC7 domain-containing protein 2. (1010 aa)    
Predicted Functional Partners:
BBOF1
Basal body-orientation factor 1 isoform X1.
      
 0.717
GPR160
Probable G-protein coupled receptor 160.
      
 0.705
RPS6KA6
Non-specific serine/threonine protein kinase.
      
 0.677
ZNFX1
NFX1-type zinc finger-containing protein 1.
      
 0.641
ARF6
ADP-ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.
    
 
 0.640
CTC1
LOW QUALITY PROTEIN: CST complex subunit CTC1.
      
 0.637
BORCS5
Loss of heterozygosity 12 chromosomal region 1 protein.
      
 0.600
DLGAP1
Disks large-associated protein 1.
   
 
 0.570
OPRL1
Nociceptin receptor; Belongs to the G-protein coupled receptor 1 family.
   
  
 0.557
AGAP2
LOW QUALITY PROTEIN: arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2.
   
 
 0.544
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.