STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RFX4Transcription factor RFX4 isoform X1. (733 aa)    
Predicted Functional Partners:
MAB21L3
Protein mab-21-like 3.
      
 0.645
RFXAP
Regulatory factor X-associated protein.
    
 
 0.611
RFX7
DNA-binding protein RFX7.
    
 
0.589
ATR
Serine/threonine-protein kinase ATR; Belongs to the PI3/PI4-kinase family.
    
 
 0.586
MARCHF3
Membrane associated ring-CH-type finger 3.
      
 0.552
TTC25
Tetratricopeptide repeat protein 25 isoform X2.
    
 
 0.548
CHEK2
Serine/threonine-protein kinase Chk2 isoform X2.
   
 
 0.519
CCDC40
Coiled-coil domain-containing protein 40.
      
 0.511
ADCYAP1R1
Pituitary adenylate cyclase-activating polypeptide type I receptor; Belongs to the G-protein coupled receptor 2 family.
   
  
 0.473
CCDC39
LOW QUALITY PROTEIN: coiled-coil domain-containing protein 39.
      
 0.457
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.