STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAP3K3Mitogen-activated protein kinase kinase kinase 3 isoform X1. (647 aa)    
Predicted Functional Partners:
ENSUMAP00000000290
annotation not available
    
 0.994
MAP2K5
Dual specificity mitogen-activated protein kinase kinase 5 isoform X2; Belongs to the protein kinase superfamily.
  
0.947
SQSTM1
Sequestosome-1.
    
 0.947
IKBKB
Inhibitor of nuclear factor kappa-B kinase subunit beta.
   
0.941
CHUK
Inhibitor of nuclear factor kappa-B kinase subunit alpha.
   
0.936
PAK2
Non-specific serine/threonine protein kinase.
  
 
0.935
PAK1
Non-specific serine/threonine protein kinase.
    
0.931
IKBKG
NF-kappa-B essential modulator.
    
 0.931
MAP2K3
Dual specificity mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily.
  
0.927
MAP2K6
Dual specificity mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily.
  
0.921
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.