STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PHACTR1Phosphatase and actin regulator. (546 aa)    
Predicted Functional Partners:
WDR37
WD repeat-containing protein 37 isoform X3.
      
 0.770
CPLX4
Complexin-4.
      
 0.750
ARMC8
Armadillo repeat-containing protein 8 isoform X1.
      
 0.742
LRRC45
Leucine-rich repeat-containing protein 45.
      
 0.729
DMXL2
LOW QUALITY PROTEIN: dmX-like protein 2.
      
 0.646
ERICH5
Glutamate-rich protein 5.
      
 0.637
RIMS1
LOW QUALITY PROTEIN: regulating synaptic membrane exocytosis protein 1.
      
 0.635
CCDC130
LOW QUALITY PROTEIN: coiled-coil domain-containing protein 130.
      
 0.583
GLRA2
Glycine receptor subunit alpha-2 isoform X2; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
      
 0.557
ALS2
Alsin Rho guanine nucleotide exchange factor ALS2.
      
 0.554
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.