STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PHLPP2PH domain leucine-rich repeat-containing protein phosphatase 2. (1317 aa)    
Predicted Functional Partners:
AKT3
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 0.959
AKT2
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 0.959
AKT1
Non-specific serine/threonine protein kinase.
    
 0.959
PHLPP1
PH domain leucine-rich repeat-containing protein phosphatase 1.
  
 
0.942
SUGT1
Suppressor of G2 allele of SKP1 homolog.
    
 
 0.693
ENSUMAP00000023597
annotation not available
    
 
 0.629
CAP1
Adenylyl cyclase-associated protein; Belongs to the CAP family.
    
 
 0.629
CAP2
Adenylyl cyclase-associated protein; Belongs to the CAP family.
    
 
 0.629
PTEN
Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.
    
 
 0.610
WDR20
WD repeat-containing protein 20 isoform X1.
    
 
 0.600
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.