STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRRC2BLOW QUALITY PROTEIN: protein PRRC2B. (2097 aa)    
Predicted Functional Partners:
G3BP2
Ras GTPase-activating protein-binding protein 2 isoform X1.
   
 
 0.802
UBAP2L
Ubiquitin-associated protein 2-like isoform X1.
   
 
 0.777
EP400
LOW QUALITY PROTEIN: E1A-binding protein p400.
   
 
 0.737
CAPRIN1
Caprin-1.
   
 
 0.656
ZNF106
Zinc finger protein 106 isoform X1.
   
  
 0.605
SH3BP5
SH3 domain-binding protein 5.
      
 0.600
AHCTF1
Protein ELYS isoform X1.
   
  
 0.558
EIF3H
Eukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...]
    
 
 0.557
CHD6
chromodomain-helicase-DNA-binding protein 6.
   
   0.546
EMSY
Protein EMSY isoform X2.
   
  
 0.545
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.