STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LYRM4LYR motif-containing protein 4; Belongs to the complex I LYR family. (91 aa)    
Predicted Functional Partners:
NFS1
Cysteine desulfurase, mitochondrial isoform X1.
   
 0.999
ISCU
Iron-sulfur cluster assembly enzyme ISCU, mitochondrial; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.
    
 0.994
ENSUMAP00000004324
annotation not available
    
 0.951
ENSUMAP00000023946
annotation not available
    
 0.951
FXN
Frataxin, mitochondrial.
    
 0.951
NDUFAB1
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
    
 
 0.911
FDX2
Adrenodoxin-like protein, mitochondrial.
   
 0.888
CIAO3
Cytosolic Fe-S cluster assembly factor NARFL; Belongs to the NARF family.
      
 0.859
SCLY
Selenocysteine lyase isoform X1.
   
 0.842
PALB2
Partner and localizer of BRCA2 isoform X1.
    
 
 0.840
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.