STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DNPEPAspartyl aminopeptidase; Belongs to the peptidase M18 family. (471 aa)    
Predicted Functional Partners:
OSBPL6
Oxysterol-binding protein; Belongs to the OSBP family.
      
 0.853
GALNT18
Polypeptide N-acetylgalactosaminyltransferase.
      
 0.849
NCAPH2
Condensin-2 complex subunit H2 isoform X1.
      
 0.800
SEZ6L
Seizure 6-like protein.
    
 
 0.750
LRRC34
Leucine-rich repeat-containing protein 34 isoform X1.
      
 0.740
ENPEP
Aminopeptidase.
      
 0.572
ATG9A
Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.
    
 
 0.552
LAP3
Leucine aminopeptidase 3.
    
 
 0.543
MRPL54
39S ribosomal protein L54, mitochondrial.
   
  
 0.525
HDAC5
Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.
      
 0.525
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.