STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSUMAP00000025788annotation not available (121 aa)    
Predicted Functional Partners:
ATP5PB
ATP synthase F(0) complex subunit B1, mitochondrial.
    
 0.747
AASS
Alpha-aminoadipic semialdehyde synthase, mitochondrial isoform X1.
      
 0.637
SLC25A12
Calcium-binding mitochondrial carrier protein Aralar1; Belongs to the mitochondrial carrier (TC 2.A.29) family.
      
 0.635
ACBD3
Golgi resident protein GCP60 isoform X2.
      
 0.599
FOXRED1
FAD-dependent oxidoreductase domain-containing protein 1 isoform X1.
   
  
 0.586
TMEM186
Transmembrane protein 186.
   
  
 0.541
ATP5PD
ATP synthase subunit d, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the cent [...]
   
 0.526
KYNU
Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity. Belongs to the kynureninase family.
      
 0.521
AASDH
acyl-CoA synthetase family member 4 isoform X1.
      
 0.521
DMAC1
Distal membrane arm assembly complex 1.
      
 0.518
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.