STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECPASProteasome-associated protein ECM29 homolog. (1942 aa)    
Predicted Functional Partners:
PSMD14
26S proteasome non-ATPase regulatory subunit 14.
   
 
 0.888
PSMC3
26S protease regulatory subunit 6A isoform X1; Belongs to the AAA ATPase family.
   
 
 0.885
PSMD12
26S proteasome non-ATPase regulatory subunit 12.
   
 
 0.865
PSMC6
26S protease regulatory subunit 10B; Belongs to the AAA ATPase family.
   
 
 0.860
PSMD8
26S proteasome non-ATPase regulatory subunit 8.
    
 
 0.857
PSMC5
26S protease regulatory subunit 8 isoform X2; Belongs to the AAA ATPase family.
   
 
 0.854
PSMD1
26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family.
   
 
 0.852
PSMD7
LOW QUALITY PROTEIN: 26S proteasome non-ATPase regulatory subunit 7.
   
 
 0.848
PSMD3
26S proteasome non-ATPase regulatory subunit 3.
   
 
 0.847
PSMD4
26S proteasome non-ATPase regulatory subunit 4.
   
 
 0.844
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.