NGLY1 protein (Ursus maritimus) - STRING interaction network

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Known Interactions

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Predicted Interactions

gene neighborhood

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textmining

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protein homology

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[Homology]

Score

NGLY1

peptide-N(4)-(N-acetyl-beta- glucosaminyl)asparagine amidase. (626 aa)

Predicted Functional Partners:

RAD23B

0.980

AMFR

0.948

UBXN1

0.940

DERL1

0.940

RAD23A

0.931

KATNAL2

0.900

VCP

0.870

PSMC1

0.848

ENSUMAP00000030720

0.848

CCDC12

0.800

Your Current Organism:

Ursus maritimus

NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AMFR	DERL1	ENSUMAP00000001597	ENSUMAP00000030370	E3 ubiquitin-protein ligase AMFR.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.996
AMFR	ENSUMAP00000030720	ENSUMAP00000001597	ENSUMAP00000030720	E3 ubiquitin-protein ligase AMFR.	annotation not available	0.802
AMFR	KATNAL2	ENSUMAP00000001597	ENSUMAP00000003140	E3 ubiquitin-protein ligase AMFR.	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.	0.681
AMFR	NGLY1	ENSUMAP00000001597	ENSUMAP00000026879	E3 ubiquitin-protein ligase AMFR.	peptide-N(4)-(N-acetyl-beta- glucosaminyl)asparagine amidase.	0.948
AMFR	PSMC1	ENSUMAP00000001597	ENSUMAP00000008616	E3 ubiquitin-protein ligase AMFR.	LOW QUALITY PROTEIN: 26S protease regulatory subunit 4; Belongs to the AAA ATPase family.	0.802
AMFR	RAD23A	ENSUMAP00000001597	ENSUMAP00000007922	E3 ubiquitin-protein ligase AMFR.	UV excision repair protein RAD23 homolog A.	0.566
AMFR	RAD23B	ENSUMAP00000001597	ENSUMAP00000019362	E3 ubiquitin-protein ligase AMFR.	LOW QUALITY PROTEIN: UV excision repair protein RAD23 homolog B.	0.882
AMFR	UBXN1	ENSUMAP00000001597	ENSUMAP00000019735	E3 ubiquitin-protein ligase AMFR.	UBX domain-containing protein 1 isoform X1.	0.947
AMFR	VCP	ENSUMAP00000001597	ENSUMAP00000008374	E3 ubiquitin-protein ligase AMFR.	Transitional endoplasmic reticulum ATPase; Belongs to the AAA ATPase family.	0.958
CCDC12	NGLY1	ENSUMAP00000005504	ENSUMAP00000026879	Coiled-coil domain-containing protein 12.	peptide-N(4)-(N-acetyl-beta- glucosaminyl)asparagine amidase.	0.800
DERL1	AMFR	ENSUMAP00000030370	ENSUMAP00000001597	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	E3 ubiquitin-protein ligase AMFR.	0.996
DERL1	ENSUMAP00000030720	ENSUMAP00000030370	ENSUMAP00000030720	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	annotation not available	0.801
DERL1	KATNAL2	ENSUMAP00000030370	ENSUMAP00000003140	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.	0.755
DERL1	NGLY1	ENSUMAP00000030370	ENSUMAP00000026879	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	peptide-N(4)-(N-acetyl-beta- glucosaminyl)asparagine amidase.	0.940
DERL1	PSMC1	ENSUMAP00000030370	ENSUMAP00000008616	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	LOW QUALITY PROTEIN: 26S protease regulatory subunit 4; Belongs to the AAA ATPase family.	0.801
DERL1	RAD23A	ENSUMAP00000030370	ENSUMAP00000007922	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	UV excision repair protein RAD23 homolog A.	0.602
DERL1	RAD23B	ENSUMAP00000030370	ENSUMAP00000019362	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	LOW QUALITY PROTEIN: UV excision repair protein RAD23 homolog B.	0.868
DERL1	UBXN1	ENSUMAP00000030370	ENSUMAP00000019735	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	UBX domain-containing protein 1 isoform X1.	0.967
DERL1	VCP	ENSUMAP00000030370	ENSUMAP00000008374	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Transitional endoplasmic reticulum ATPase; Belongs to the AAA ATPase family.	0.983
ENSUMAP00000030720	AMFR	ENSUMAP00000030720	ENSUMAP00000001597	annotation not available	E3 ubiquitin-protein ligase AMFR.	0.802