STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADAM15Disintegrin and metalloproteinase domain-containing protein 15. (772 aa)    
Predicted Functional Partners:
CDH1
Cadherin-1; Cadherins are calcium-dependent cell adhesion proteins.
    
 0.875
INSR
Tyrosine-protein kinase receptor.
    
 
 0.642
TYRO3
Tyrosine-protein kinase receptor TYRO3.
    
 
 0.638
SNX9
Sorting nexin.
    
 
 0.622
CNNM2
Metal transporter CNNM2.
   
  
 0.606
SH3PXD2A
LOW QUALITY PROTEIN: SH3 and PX domain-containing protein 2A.
    
 0.597
PTPRF
LOW QUALITY PROTEIN: receptor-type tyrosine-protein phosphatase F.
   
 
 0.587
PTPRF-2
Protein tyrosine phosphatase, receptor type F.
   
 
 0.587
ITGA7
Integrin alpha-7; Belongs to the integrin alpha chain family.
    
 
 0.581
RBL1
RB transcriptional corepressor like 1.
      
 0.540
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
Server load: low (26%) [HD]