STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (304 aa)    
Predicted Functional Partners:
LOC103657720
Protein phosphatase 1 regulatory subunit.
   
 0.996
PPP1R12A
Protein phosphatase 1 regulatory subunit.
   
 0.996
LOC103657721
Protein phosphatase 1 regulatory subunit 12B-like.
   
 0.970
PPP1R3A
Protein phosphatase 1 regulatory subunit 3A.
    
 0.966
EIF2S1
Eukaryotic translation initiation factor 2 subunit alpha.
   
 0.959
RB1
Retinoblastoma-associated protein.
   
 0.956
PPP1CC
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
  
0.955
PPP1CA
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
  
0.954
PPP1R3C
Protein phosphatase 1 regulatory subunit 3C; Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown.
    
 0.946
PPP1R3B
Protein phosphatase 1 regulatory subunit.
    
 0.946
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.