STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DOP1BProtein dopey-2. (2286 aa)    
Predicted Functional Partners:
MON2
MON2 homolog, regulator of endosome-to-Golgi trafficking.
   
 
 0.867
KIAA0355
LOW QUALITY PROTEIN: uncharacterized protein KIAA0355 homolog.
      
 0.770
RESF1
LOW QUALITY PROTEIN: uncharacterized protein KIAA1551 homolog.
      
 0.762
RSAD1
Radical S-adenosyl methionine domain-containing protein; May be a heme chaperone, appears to bind heme. Homologous bacterial proteins do not have oxygen-independent coproporphyrinogen- III oxidase activity. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L- methionine; Belongs to the anaerobic coproporphyrinogen-III oxidase family.
      
 0.724
MRPS6
28S ribosomal protein S6, mitochondrial isoform X2.
      
 0.649
TBATA
Protein TBATA.
      
 0.641
TMEM50B
Transmembrane protein 50B.
      
 0.636
DPM1
Dolichol-phosphate mannosyltransferase subunit 1; Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins.
      
 0.636
GET1
Guided entry of tail-anchored proteins factor 1.
      
 0.602
PAXBP1
PAX3- and PAX7-binding protein 1.
      
 0.577
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.