STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSUMAP00000028845annotation not available (125 aa)    
Predicted Functional Partners:
HAT1
Histone acetyltransferase type B catalytic subunit; Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG.
    
 0.703
MYSM1
Histone H2A deubiquitinase MYSM1 isoform X1.
    
 0.687
ARID4B
AT-rich interactive domain-containing protein 4B.
    
 0.665
ARID4A
AT-rich interactive domain-containing protein 4A isoform X3.
    
 0.665
KDM6A
Lysine-specific demethylase 6A.
   
 0.630
LOC103680203
LOW QUALITY PROTEIN: lysine-specific demethylase 6A-like.
   
 0.630
RBBP5
RB binding protein 5, histone lysine methyltransferase complex subunit.
    
 0.613
RPS27A
ubiquitin-40S ribosomal protein S27a.
   
 0.609
ORC1
Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
    
 0.600
ASH2L
ASH2 like, histone lysine methyltransferase complex subunit.
    
 0.590
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.