STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDH5LOW QUALITY PROTEIN: cadherin-5; Cadherins are calcium-dependent cell adhesion proteins. (720 aa)    
Predicted Functional Partners:
CTNNB1
Catenin beta-1.
    
 0.999
PECAM1
Platelet endothelial cell adhesion molecule isoform X1.
   
 0.999
CTNND1
Catenin delta-1 isoform X1.
    
 0.996
KDR
LOW QUALITY PROTEIN: vascular endothelial growth factor receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
   
 0.932
JUP
Junction plakoglobin.
    
 0.841
ENSUMAP00000007874
annotation not available
    
 0.818
CTNNA2
Catenin alpha 2.
    
 0.818
CTNNA1
Catenin alpha-1.
    
 0.818
PARD3
Partitioning defective 3 homolog isoform X2.
    
 
 0.806
VWF
Von Willebrand factor.
   
 
 0.788
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.