STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLEKPleckstrin isoform X2. (350 aa)    
Predicted Functional Partners:
OSBP
Oxysterol-binding protein; Belongs to the OSBP family.
   
  
 0.787
BIN1
Myc box-dependent-interacting protein 1 isoform X14.
   
 
 0.740
CDC42
Cell division control protein 42 homolog isoform X1.
   
 
 0.663
ENSUMAP00000021933
annotation not available
   
 
 0.663
SRC
Tyrosine-protein kinase.
   
  
 0.659
PLCD1
Phosphoinositide phospholipase C.
      
 0.646
ANGPTL8
Angiopoietin like 8.
      
 0.637
RABIF
Guanine nucleotide exchange factor MSS4.
      
 0.636
MYO10
LOW QUALITY PROTEIN: unconventional myosin-X; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
      
 0.636
EEA1
Early endosome antigen 1.
      
 0.635
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.