STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MACF1-2Microtubule-actin crosslinking factor 1. (1062 aa)    
Predicted Functional Partners:
DST
Dystonin isoform X1.
 
 
    0.907
MACF1
Microtubule-actin cross-linking factor 1.
 
      0.900
ENSUMAP00000029233
annotation not available
 
 
    0.877
ITGB4
Integrin beta.
   
 0.631
UHRF1BP1
UHRF1-binding protein 1.
      
 0.600
C1orf74
Chromosome 1 open reading frame 74.
      
 0.583
JUP
Junction plakoglobin.
   
 0.553
MFN2
Mitofusin-2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
   
 
 0.540
CSMD2
CUB and sushi domain-containing protein 2.
    
 0.520
DIO3
Iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine).
      
 0.515
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.