STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARHGAP44Rho GTPase-activating protein 44. (544 aa)    
Predicted Functional Partners:
ACKR4
Atypical chemokine receptor 4 isoform X1; Belongs to the G-protein coupled receptor 1 family.
   
  
 0.736
MSR1
Macrophage scavenger receptor types I and II isoform X1.
      
 0.729
NCOA3
Nuclear receptor coactivator.
      
 0.698
STAG2
Cohesin subunit SA-2.
   
  
 0.639
FCHSD1
FCH and double SH3 domains protein 1.
    
 0.575
FCHSD2
FCH and double SH3 domains protein 2 isoform X2.
    
 0.549
ARHGEF37
Rho guanine nucleotide exchange factor 37.
      
 0.540
STK10
Serine/threonine-protein kinase 10.
      
 0.539
NFIB
Nuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.
      
 0.533
ARHGEF38
Rho guanine nucleotide exchange factor 38.
      
 0.525
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.