STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FAM189A2Family with sequence similarity 189 member A2. (450 aa)    
Predicted Functional Partners:
DNASE2B
Deoxyribonuclease-2-beta.
      
 0.739
CDK18
Cyclin-dependent kinase 18 isoform X2; Belongs to the protein kinase superfamily.
   
 
 0.685
BLK
Tyrosine-protein kinase.
   
 0.603
RAB3IP
rab-3A-interacting protein.
    
 0.594
GNS
N-acetylglucosamine-6-sulfatase; Belongs to the sulfatase family.
   
  
 0.521
EXOC4
Exocyst complex component 4 isoform X1.
    
 0.496
EXOC1
LOW QUALITY PROTEIN: exocyst complex component 1-like.
   
 0.485
GDI2
Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.
   
 0.479
GDI1
Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.
   
 0.479
ENSUMAP00000030311
annotation not available
   
 0.479
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.