STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CX3CL1C-X3-C motif chemokine ligand 1. (412 aa)    
Predicted Functional Partners:
CX3CR1
C-X3-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family.
    
 0.999
CCR2
C-C motif chemokine receptor 2; Belongs to the G-protein coupled receptor 1 family.
    
 0.953
CCR5
C-C motif chemokine receptor 5 (gene/pseudogene); Belongs to the G-protein coupled receptor 1 family.
    
 0.931
CCR7
LOW QUALITY PROTEIN: C-C chemokine receptor type 7; Belongs to the G-protein coupled receptor 1 family.
    
 0.918
CXCR4
C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family.
    
 0.910
CCR8
C-C motif chemokine receptor 8; Belongs to the G-protein coupled receptor 1 family.
    
 0.883
CCR3
C-C chemokine receptor type 3 isoform X1; Belongs to the G-protein coupled receptor 1 family.
    
 0.876
CXCL12
Stromal cell-derived factor 1; Belongs to the intercrine alpha (chemokine CxC) family.
   
 0.875
LOC103662893
C-X-C chemokine receptor type 2.
    
 0.855
LOC103662772
LOW QUALITY PROTEIN: C-X-C chemokine receptor type 2-like; Belongs to the G-protein coupled receptor 1 family.
    
 0.855
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.