RETREG1 protein (Ursus maritimus) - STRING interaction network

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Score

RETREG1

Protein FAM134B isoform X3. (356 aa)

Predicted Functional Partners:

LSG1

0.917

NMD3

0.910

PA2G4

0.873

EIF6

0.864

RPL24

0.796

RSL24D1

0.771

RPL5

0.767

GNL1

0.754

RPL11

0.752

RPL19

0.750

Your Current Organism:

Ursus maritimus

NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EIF6	GNL1	ENSUMAP00000006505	ENSUMAP00000025981	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...]	Guanine nucleotide-binding protein-like 1.	0.863
EIF6	LSG1	ENSUMAP00000006505	ENSUMAP00000000794	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...]	Large 60S subunit nuclear export GTPase 1.	0.965
EIF6	NMD3	ENSUMAP00000006505	ENSUMAP00000015028	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...]	60S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family.	0.971
EIF6	PA2G4	ENSUMAP00000006505	ENSUMAP00000022974	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...]	Proliferation-associated protein 2G4.	0.968
EIF6	RETREG1	ENSUMAP00000006505	ENSUMAP00000030026	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...]	Protein FAM134B isoform X3.	0.864
EIF6	RPL11	ENSUMAP00000006505	ENSUMAP00000017982	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...]	60S ribosomal protein L11; Belongs to the universal ribosomal protein uL5 family.	0.965
EIF6	RPL19	ENSUMAP00000006505	ENSUMAP00000023645	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...]	Ribosomal protein L19; Belongs to the eukaryotic ribosomal protein eL19 family.	0.970
EIF6	RPL24	ENSUMAP00000006505	ENSUMAP00000004006	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...]	60S ribosomal protein L24.	0.976
EIF6	RPL5	ENSUMAP00000006505	ENSUMAP00000015109	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...]	60S ribosomal protein L5 isoform X1.	0.977
EIF6	RSL24D1	ENSUMAP00000006505	ENSUMAP00000032503	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...]	Probable ribosome biogenesis protein RLP24.	0.977
GNL1	EIF6	ENSUMAP00000025981	ENSUMAP00000006505	Guanine nucleotide-binding protein-like 1.	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...]	0.863
GNL1	NMD3	ENSUMAP00000025981	ENSUMAP00000015028	Guanine nucleotide-binding protein-like 1.	60S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family.	0.930
GNL1	PA2G4	ENSUMAP00000025981	ENSUMAP00000022974	Guanine nucleotide-binding protein-like 1.	Proliferation-associated protein 2G4.	0.889
GNL1	RETREG1	ENSUMAP00000025981	ENSUMAP00000030026	Guanine nucleotide-binding protein-like 1.	Protein FAM134B isoform X3.	0.754
GNL1	RPL11	ENSUMAP00000025981	ENSUMAP00000017982	Guanine nucleotide-binding protein-like 1.	60S ribosomal protein L11; Belongs to the universal ribosomal protein uL5 family.	0.743
GNL1	RPL19	ENSUMAP00000025981	ENSUMAP00000023645	Guanine nucleotide-binding protein-like 1.	Ribosomal protein L19; Belongs to the eukaryotic ribosomal protein eL19 family.	0.692
GNL1	RPL24	ENSUMAP00000025981	ENSUMAP00000004006	Guanine nucleotide-binding protein-like 1.	60S ribosomal protein L24.	0.788
GNL1	RPL5	ENSUMAP00000025981	ENSUMAP00000015109	Guanine nucleotide-binding protein-like 1.	60S ribosomal protein L5 isoform X1.	0.844
GNL1	RSL24D1	ENSUMAP00000025981	ENSUMAP00000032503	Guanine nucleotide-binding protein-like 1.	Probable ribosome biogenesis protein RLP24.	0.855
LSG1	EIF6	ENSUMAP00000000794	ENSUMAP00000006505	Large 60S subunit nuclear export GTPase 1.	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...]	0.965