STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HYAL3Hyaluronidase. (417 aa)    
Predicted Functional Partners:
ARSB
Arylsulfatase B.
   
 0.913
ITSN2
LOW QUALITY PROTEIN: intersectin-2.
    
 0.800
CD44
CD44 antigen isoform X7.
    
 0.749
ALB
Serum albumin isoform X1.
      
 0.718
ITSN1
Intersectin-1 isoform X2.
    
 0.698
ENSUMAP00000027695
annotation not available
    
 0.698
INS-IGF2
Insulin, isoform 2-like; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
     
 0.636
ACAN
LOW QUALITY PROTEIN: aggrecan core protein.
    
 0.627
GAK
LOW QUALITY PROTEIN: cyclin-G-associated kinase.
   
 0.619
GAK-2
Cyclin G associated kinase.
   
 0.619
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.