CTLA4 protein (Ursus maritimus) - STRING interaction network

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

CTLA4

Cytotoxic T-lymphocyte associated protein 4. (223 aa)

Predicted Functional Partners:

CD86

0.999

CD80

0.999

PTPN6

0.957

ICOSLG

0.936

CD274

0.901

ICOS

0.899

CD40

0.830

LAG3

0.822

CD40LG

0.817

CD4

0.815

Your Current Organism:

Ursus maritimus

NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD274	CD4	ENSUMAP00000022876	ENSUMAP00000006361	Programmed cell death 1 ligand 1.	T-cell surface glycoprotein CD4.	0.849
CD274	CD40	ENSUMAP00000022876	ENSUMAP00000034917	Programmed cell death 1 ligand 1.	Tumor necrosis factor receptor superfamily member 5 isoform X5.	0.638
CD274	CD40LG	ENSUMAP00000022876	ENSUMAP00000014138	Programmed cell death 1 ligand 1.	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	0.455
CD274	CD80	ENSUMAP00000022876	ENSUMAP00000035165	Programmed cell death 1 ligand 1.	T-lymphocyte activation antigen CD80.	0.998
CD274	CD86	ENSUMAP00000022876	ENSUMAP00000035089	Programmed cell death 1 ligand 1.	T-lymphocyte activation antigen CD86 isoform X1.	0.574
CD274	CTLA4	ENSUMAP00000022876	ENSUMAP00000030761	Programmed cell death 1 ligand 1.	Cytotoxic T-lymphocyte associated protein 4.	0.901
CD274	ICOS	ENSUMAP00000022876	ENSUMAP00000030771	Programmed cell death 1 ligand 1.	Inducible T-cell costimulator isoform X1.	0.747
CD274	LAG3	ENSUMAP00000022876	ENSUMAP00000006422	Programmed cell death 1 ligand 1.	Lymphocyte activation gene 3 protein.	0.747
CD274	PTPN6	ENSUMAP00000022876	ENSUMAP00000005099	Programmed cell death 1 ligand 1.	Tyrosine-protein phosphatase non-receptor type 6.	0.500
CD4	CD274	ENSUMAP00000006361	ENSUMAP00000022876	T-cell surface glycoprotein CD4.	Programmed cell death 1 ligand 1.	0.849
CD4	CD40	ENSUMAP00000006361	ENSUMAP00000034917	T-cell surface glycoprotein CD4.	Tumor necrosis factor receptor superfamily member 5 isoform X5.	0.783
CD4	CD40LG	ENSUMAP00000006361	ENSUMAP00000014138	T-cell surface glycoprotein CD4.	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	0.833
CD4	CD80	ENSUMAP00000006361	ENSUMAP00000035165	T-cell surface glycoprotein CD4.	T-lymphocyte activation antigen CD80.	0.814
CD4	CD86	ENSUMAP00000006361	ENSUMAP00000035089	T-cell surface glycoprotein CD4.	T-lymphocyte activation antigen CD86 isoform X1.	0.783
CD4	CTLA4	ENSUMAP00000006361	ENSUMAP00000030761	T-cell surface glycoprotein CD4.	Cytotoxic T-lymphocyte associated protein 4.	0.815
CD4	ICOS	ENSUMAP00000006361	ENSUMAP00000030771	T-cell surface glycoprotein CD4.	Inducible T-cell costimulator isoform X1.	0.776
CD4	LAG3	ENSUMAP00000006361	ENSUMAP00000006422	T-cell surface glycoprotein CD4.	Lymphocyte activation gene 3 protein.	0.644
CD4	PTPN6	ENSUMAP00000006361	ENSUMAP00000005099	T-cell surface glycoprotein CD4.	Tyrosine-protein phosphatase non-receptor type 6.	0.603
CD40	CD274	ENSUMAP00000034917	ENSUMAP00000022876	Tumor necrosis factor receptor superfamily member 5 isoform X5.	Programmed cell death 1 ligand 1.	0.638
CD40	CD4	ENSUMAP00000034917	ENSUMAP00000006361	Tumor necrosis factor receptor superfamily member 5 isoform X5.	T-cell surface glycoprotein CD4.	0.783