STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CA4Carbonic anhydrase 4 isoform X3; Belongs to the alpha-carbonic anhydrase family. (323 aa)    
Predicted Functional Partners:
CA14
Carbonic anhydrase 14; Belongs to the alpha-carbonic anhydrase family.
  
  
0.598
CA9
Carbonic anhydrase 9; Belongs to the alpha-carbonic anhydrase family.
  
  
0.598
CA12
Carbonic anhydrase 12; Belongs to the alpha-carbonic anhydrase family.
  
  
0.583
RPF2
Ribosome production factor 2 homolog.
   
 
 0.570
CRISP1
Cysteine-rich secretory protein 1; Belongs to the CRISP family.
   
  
 0.526
PLCB2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
      
 0.521
RD3
Retinal degeneration 3, GUCY2D regulator.
      
 0.517
MAP2
Microtubule-associated protein.
    
 
 0.501
GFAP
Glial fibrillary acidic protein; Belongs to the intermediate filament family.
   
 
 0.491
ALB
Serum albumin isoform X1.
   
 
 0.466
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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