STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ITGB8Integrin beta; Belongs to the integrin beta chain family. (720 aa)    
Predicted Functional Partners:
ITGAV
LOW QUALITY PROTEIN: integrin alpha-V; Belongs to the integrin alpha chain family.
   
 0.999
TLN2
Talin-2.
   
 0.986
VTN
Vitronectin.
    
 0.979
SRC
Tyrosine-protein kinase.
    
 0.967
PTK2
Focal adhesion kinase 1 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family.
   
 0.955
ITGA4
Integrin alpha-4 isoform X2; Belongs to the integrin alpha chain family.
   
 0.954
FLNB
filamin-B isoform X2.
    
 0.951
ITGA6
LOW QUALITY PROTEIN: integrin alpha-6; Belongs to the integrin alpha chain family.
   
 0.945
ITGA9
Integrin alpha-9; Belongs to the integrin alpha chain family.
   
 0.944
ITGA2B
Integrin subunit alpha 2b; Belongs to the integrin alpha chain family.
   
 0.944
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.