STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SLC25A28Mitoferrin-2; Belongs to the mitochondrial carrier (TC 2.A.29) family. (323 aa)    
Predicted Functional Partners:
NARS2
Probable asparagine--tRNA ligase, mitochondrial isoform X1.
 
      0.898
METTL1
tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
 
 
    0.702
CALCOCO2
Calcium-binding and coiled-coil domain-containing protein 2.
      
 0.599
RRP9
U3 small nucleolar RNA-interacting protein 2.
      
 0.570
MRPL4
39S ribosomal protein L4, mitochondrial isoform X2.
    
 
 0.569
ADGRF2
Probable G-protein coupled receptor 111; Belongs to the G-protein coupled receptor 2 family.
      
 0.541
FECH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX.
   
  
 0.533
ABCB7
ATP-binding cassette sub-family B member 7, mitochondrial.
    
 
 0.533
SLC35B1
Solute carrier family 35 member B1.
    
 
 0.528
ISCU
Iron-sulfur cluster assembly enzyme ISCU, mitochondrial; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.
   
  
 0.522
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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