STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAK3Non-specific serine/threonine protein kinase. (554 aa)    
Predicted Functional Partners:
ARHGEF6
LOW QUALITY PROTEIN: rho guanine nucleotide exchange factor 6.
    
 0.952
CDC42
Cell division control protein 42 homolog isoform X1.
   
 0.932
ENSUMAP00000021933
annotation not available
   
 0.932
GIT2
ARF GTPase-activating protein GIT2.
    
 0.916
GIT1
ARF GTPase-activating protein GIT1.
    
 0.886
RAC1
Ras-related C3 botulinum toxin substrate 1.
   
 0.874
ITSN2
LOW QUALITY PROTEIN: intersectin-2.
    
 0.790
ARHGEF7
Rho guanine nucleotide exchange factor 7 isoform X2.
    
 0.761
NCK1
NCK adaptor protein 1.
    
 0.702
RAC2
Ras-related C3 botulinum toxin substrate 2.
   
 0.691
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.